A Facile One Pot Microwave Synthesis Of 2-Amino-5- Aryl Thiazole By Using NaHSO4-SiO2 Heterogenous Catalyst In Dry Media
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چکیده
The new novel series of 2-amino-5-phenyl thiazole derivatives were occurred in the reaction between thiourea and various substituted ketones. The reactions were carried out in the microwave oven under solvent free condition. The completion of the reactions was checked by TLC. The structures of the compounds were characterized by FT-IR, 1 H and 13 C NMR and elemental analysis. Synthesized compound were checked by their drug ability by using Lipinski’s rule.
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